Ankur Sharma, PhD — Computational biologist and agentic AI engineer, Singapore.

I build systems that connect genomic data to real-world decisions: outbreak surveillance, precision diagnostics, and autonomous research pipelines.

Full portfolio: ankurgenomics.github.io/agentic-genomics/

Background

  • PhD in computational biology / bioinformatics, NTU Singapore
  • 8+ years building production ML and genomic data pipelines in clinical and research settings
  • Current focus: agentic AI systems for high-stakes biological decisions

Projects

  • Reviewer2 — Autonomous ACMG/AMP variant second reviewer. 4-node LangGraph pipeline exposed as an MCP server. 21 tests, 86% action-band concordance vs expert-panel ClinVar.
  • sentinel-amr — Explainable AMR classifier for bacterial surveillance. XGBoost + SHAP + LangGraph. ROC-AUC 0.894 on a group-aware holdout. Detects novel organisms and escalates before trusting the model.
  • outbreak-agent — LangGraph triage pipeline for infectious disease surveillance. 33 tests, no API key required.
  • agentic-genomics — Reasoning-traceable variant interpretation agent. VCF + HPO → ranked ACMG candidates with full audit trail.
  • genomics-skills — 8 agent-callable genomics tools: TCGA expression, survival, enrichment, PubMed, protein mapping.

Contact